The Estates Committee of the Ministry of Justice – the Administrator General and the Supervisor of Inheritance Affairs – has approved Prof. Ofer Reany’s proposal from the Department of Natural Sciences for funding a groundbreaking research project in the field of supramolecular chemistry through an endowment fund designated for research in the fields of engineering and exact sciences. The project, with a budget of approximately ₪350,000, focuses on developing unique molecules known as Bambusurils, which function as synthetic non-protein anion channels and chloride transport carriers.
The goal of the research is to design and synthesize advanced systems capable of transporting chloride ions across biological membranes, thereby laying the foundation for innovative therapies for diseases caused by genetic mutations or immune deficiencies that impair ion channel function (channelopathies). Additionally, the project aims to develop novel cancer treatment strategies by disrupting ionic and pH balance within cancer cells. This work combines fundamental research with future biomedical applications, including the development of systems responsive to biological stimuli and physiological conditions.
The potential impact of this research is significant: establishing a new diagnostic and therapeutic platform, advancing the field of ion transport, and expanding scientific knowledge in this area. Securing funding from the Estates Fund reflects recognition of the scientific and societal importance of this project and will enable cutting-edge experiments, international collaborations, and the training of the next generation of researchers.