Podcasts

These podcasts were created using Google Notebook LM, a large language model from Google AI. The content is based on peer-reviewed research published by Doron's Lab:
  

"Unpredictable Stress, Lasting Impact: Cognition and the Adolescent Brain"

Based on: "Imbalance in Sirt1 alternative splicing in response to chronic stress during the adolescence period (2022)"
https://www.openu.ac.il/psychobiology-mp3/Long-Term.mp3

"Beyond SSRIs: Exploring Shan Zha as a Herbal Treatment for Anxiety and Depression"

Based on: "Anxiolytic and antidepressants’ effect of Crataegus pinnatifida (Shan Zha): biochemical mechanisms (2022)"
https://www.openu.ac.il/psychobiology-mp3/Shan-Zha.mp3

Rejuvenating the Aging Brain: Ultra-Low Dose THC as a Potential Therapy for age-related cognitive decline and Alzheimer's disease.

Based on: "An ultra-low dose of ∆9-tetrahydrocannabinol alleviates Alzheimer’s disease-related cognitive impairments and modulates TrkB receptor expression in 5XFAD mouse model (2022)" and "Reversal of age-related cognitive impairments in mice by an extremely low dose of tetrahydrocannabinol (2018).
https://www.openu.ac.il/psychobiology-mp3/Ultra-Low.mp3

Publications

2024

Bregman-Yemini*, N., Nitzan, K*., Franko, M., & Doron, R. (2024)

Connecting the Emotional-Cognitive Puzzle: The Role of Tyrosine Kinase (TrkB) Receptor Isoform Imbalance in Age-Related Emotional and Cognitive impairments

Ageing Research Reviews, 102349. *Equal contribution. https://doi.org/10.1016/j.arr.2024.102349
Shchory S,* Nitzan K* , Harpaz G & Doron R (2024)

Not Just a Game: The Effect of Active Versus Passive Virtual Reality Experiences on Anxiety and Sadness

VVirtual Reality 28, 20. *Equal contribution.  https://doi.org/10.1007/s10055-023-00925-6

2023

Nitzan K, Frenkel D, Parker M, Doron R (2023)

Editorial: Alzheimer-Related Affective Symptoms -Mechanism and Treatment

Frontiers in Aging Neuroscience. https://doi.org/10.3389/fpsyt.2023.1197763

2022

Shamir A, Dabbah-Assadi, Rashid Sally; Golani I, Rubinstein A, Doron, R, Alon D, Palzur E, Beloosesky R (2022)

Long-Term Effects of prophylactic MgSO 4 in Maternal Immune Activation Rodent Model at Adolescence and Adulthood

Journal of Neuroscience Research. Volume101, Issue 3; https://doi.org/10.1002/jnr.25148
Nitzan K, Ellenbogen L, Bentulila Z, David D, Franko M, Break E, Zoharetz M, Shamir A, SarneY, Doron R (2022)

An ultra-low dose of ∆9-tetrahydrocannabinol alleviates Alzheimer’s disease-related cognitive impairments and modulates TrkB receptor expression in 5XFAD mouse model

International Journal of Molecular Sciences. 23(16), 9449; https://doi.org/10.3390/ijms23169449
Nitzan K, Parker M, Shamir A, Chen G and Doron R (2022)

Editorial of 'The Burden of Stress and Depression – New Insight into Faster and Efficient Treatment

Frontiers In Behavioral Neuroscience, Volume 16; https://doi.org/10.3389/fnbeh.2022.998307
Clay J., Fontana B, Proserpio C, Fernandez E, Pagliarini E, Lopes F, López-Moreno J, Canales J, Loyant L, Doron R, Stafford L, Parker M (2022)

Drinking During Social Isolation: Investigating Associations Between, Stress, Inhibitory Control, Boredom, Drinking Motives and Alcohol Use 

Addiction Research & Theory, 31(1), 16–28; https://doi.org/10.1080/16066359.2022.2099543
Avraham E ,Sacher Y,  Maaravi Hesseg R,  Karni  A,  Doron R (2022)

Skill learning by observation –training patients after traumatic brain injury

Frontiers Human Neuroscience, Volume 16; https://doi.org/10.3389/fnhum.2022.940075
Nitzan K, David D,  Franko M, Toledano R, Fidelman S,Simchon Y, Blonder M, Armoza S,  Shamir A,   Rehavi M, Ben-chaim Y, Doron R.(2022) 

Anxiolytic and antidepressants’ effect of Crataegus pinnatifida (Shan Zha): biochemical mechanisms

Translational Psychiatry 12. https://doi.org/10.1038/s41398-022-01970-6
Shlomi S, Toledano R, Shahaf S, Nitzan K, Frenkel D, Doron R (2022)

Imbalance in Sirt1 alternative splicing in response to chronic stress during the adolescence period

International Journal of Molecular Sciences23(9), 4945; https://doi.org/10.3390/ijms23094945

2021

Burstein, O., Simon, N., Simchon-Tenenbaum, Y., Rehavi, M., Franko, M., Shamir, A., & Doron, R. (2021)

Moderation of the transgenerational transference of antenatal stress-induced anxiety

Translational Psychiatry, 11(1), 1–10. https://doi.org/10.1038/s41398-021-01383-x
Gilboa, D., Seidman, L., Kimiagarov, P., Noni, A., Doron, R., & Seidman, D. S. (2021)

Why do women choose to undergo oocyte aspiration without sedation or analgesia?

Reproduction and Fertility, 2(2), 89–94. https://doi.org/10.1530/RAF-20-0064
Nitzan, K., Toledano, R., Shapira, S., Arber, N., & Doron, R. (2021)

Behavioral Characterizing of CD24 Knockout Mouse—Cognitive and Emotional Alternations

Journal of Personalized Medicine, 11(2), 105. https://doi.org/10.3390/jpm11020105
Burstein, O., Shamir, A., Abramovitz, N., & Doron, R. (2021)

Patients’ attitudes toward conventional and herbal treatments for depression and anxiety: A cross-sectional Israeli survey

International Journal of Social Psychiatry. https://doi.org/10.1177/0020764021992385

2020

Alteba, S., Mizrachi Zer-Aviv, T., Tenenhaus, A., Ben David, G., Adelman, J., Hillard, C. J., Doron, R., & Akirav, I. (2020)

Antidepressant-like effects of URB597 and JZL184 in male and female rats exposed to early life stress

European Neuropsychopharmacology, 39, 70–86. https://doi.org/10.1016/j.euroneuro.2020.08.005

2019

Doron, R., Versano, Z., Burstein, O., Franko, M., Shamir, A., Toledano, R., Handelsman, A., & Rehavi, M.(2019)

Cerebral MAO Activity Is Not Altered by a Novel Herbal Antidepressant Treatment

Journal of Molecular Neuroscience, 69(3), 371–379. https://doi.org/10.1007/s12031-019-01366-0
Dabbah-Assadi, F., Alon, D., Golani, I., Doron, R., Kremer, I., Beloosesky, R., & Shamir, A. (2019)

The influence of immune activation at early vs late gestation on fetal NRG1-ErbB4 expression and behavior in juvenile and adult mice offspring

Brain, Behavior, and Immunity, 79, 207–215. https://doi.org/10.1016/j.bbi.2019.02.002

2018

Burstein, O., & Doron, R. (2018)

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Journal of Visualized Experiments, 140, 58184. https://doi.org/10.3791/58184
Doron, R., Sever, A., Handelsman, A., Toledano, R., Franko, M., Hirshler, Y., Shamir, A., Burstein, O., & Rehavi, M. (2018)

GABAA Receptor Density Is Not Altered by a Novel Herbal Anxiolytic Treatment

Journal of Molecular Neuroscience, 65(1), 110–117. https://doi.org/10.1007/s12031-018-1078-2
Burstein, O*., Shoshan, N., Doron, R*., & Akirav, I*. (2018)

Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 84, 129–139. https://doi.org/10.1016/j.pnpbp.2018.01.026 *Equal contribution.
Sarne, Y., Toledano, R., Rachmany, L., Sasson, E., & Doron, R. (2018)

Reversal of age-related cognitive impairments in mice by an extremely low dose of tetrahydrocannabinol

Neurobiology of Aging, 61, 177–186. https://doi.org/10.1016/j.neurobiolaging.2017.09.025
Tadmor, H., Golani, I., Doron, R., Kremer, I., & Shamir, A. (2018)

ErbB signaling antagonist ameliorates behavioral deficit induced by phencyclidine (PCP) in mice, without affecting metabolic syndrome markers

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 82, 322–331. https://doi.org/10.1016/j.pnpbp.2017.08.010

2017

Burstein, O., Franko, M., Gale, E., Handelsman, A., Barak, S., Motsan, S., Shamir, A., Toledano, R., Simhon, O., Hirshler, Y., Chen, G., & Doron, R. (2017)

Escitalopram and NHT normalized stress-induced anhedonia and molecular neuroadaptations in a mouse model of depression

PLOS ONE, 12(11), e0188043. https://doi.org/10.1371/journal.pone.0188043
Hirshler, Y., & Doron, R. (2017)

Neuroplasticity-related mechanisms underlying the antidepressant-like effects of traditional herbal medicines

European Neuropsychopharmacology, 27(10), 945–958. https://doi.org/10.1016/j.euroneuro.2017.07.008
Avitsur, R., Paley, S., Franko, M., Wolff, N., Eyal, N., & Doron, R. (2017)

Escitalopram or novel herbal treatments differentially alter cytokine and behavioral responses to immune challenge

Journal of Neuroimmunology, 309, 111–118. https://doi.org/10.1016/j.jneuroim.2017.05.020

2016

Wu, R., Tao, W., Zhang, H., Xue, W., Zou, Z., Wu, H., Cai, B., Doron, R., & Chen, G. (2016)

Instant and Persistent Antidepressant Response of Gardenia Yellow Pigment Is Associated with Acute Protein Synthesis and Delayed Upregulation of BDNF Expression in the Hippocampus.

ACS Chemical Neuroscience, 7(8), 1068–1076. https://doi.org/10.1021/acschemneuro.6b00011
Xia, B., Zhang, H., Xue, W., Tao, W., Chen, C., Wu, R., Ren, L., Tang, J., Wu, H., Cai, B., Doron, R., & Chen, G. (2016)

Instant and Lasting Down-Regulation of NR1 Expression in the Hippocampus is Associated Temporally with Antidepressant Activity After Acute Yueju.

Cellular and Molecular Neurobiology, 36(7), 1189–1196. https://doi.org/10.1007/s10571-015-0316-1

2015

Yankelevitch-Yahav, R., Franko, M., Huly, A., & Doron, R. (2015)

The Forced Swim Test as a Model of Depressive-like Behavior

Journal of Visualized Experiments, 97, 52587. https://doi.org/10.3791/52587

2014

Doron, R., Lotan, D., Versano, Z., Benatav, L., Franko, M., Armoza, S., Kately, N., & Rehavi, M. (2014)

Escitalopram or novel herbal mixture treatments during or following exposure to stress reduce anxiety-like behavior through corticosterone and BDNF modifications

PloS One, 9(4), e91455. https://doi.org/10.1371/journal.pone.0091455
Doron, R., Lotan, D., Einat, N., Yaffe, R., Winer, A., Marom, I., Meron, G., Kately, N., & Rehavi, M. (2014)

A novel herbal treatment reduces depressive-like behaviors and increases BDNF levels in the brain of stressed mice

Life Sciences, 94(2), 151–157. https://doi.org/10.1016/j.lfs.2013.10.025

2002-2012

Yadid, G., Redlus, L., Barnea, R., & Doron, R. (2012)

Modulation of Mood States as a Major Factor in Relapse to Substance Use

Frontiers in Molecular Neuroscience, 5, 81. https://doi.org/10.3389/fnmol.2012.00081
Doron, R., Lotan, D., Rak-Rabl, A., Raskin-Ramot, A., Lavi, K., & Rehavi, M. (2012)

Anxiolytic effects of a novel herbal treatment in mice models of anxiety

Life Sciences, 90(25–26), 995–1000. https://doi.org/10.1016/j.lfs.2012.05.014
Doron, R., Fridman, L., Gispan-Herman, I., Maayan, R., Weizman, A., & Yadid, G. (2006)

DHEA, a Neurosteroid, Decreases Cocaine Self-Administration and Reinstatement of Cocaine-Seeking Behavior in Rats

Neuropsychopharmacology, 31(10), 2231–2236. https://doi.org/10.1038/sj.npp.1301013
Doron, R., Fridman, L., & Yadid, G. (2006)

Dopamine-2 receptors in the arcuate nucleus modulate cocaine-seeking behavior

NeuroReport, 17(15), 1633–1636. https://doi.org/10.1097/01.wnr.0000234755.88560.c7
Maayan, R., Lotan, S., Doron, R., Shabat-Simon, M., Gispan-Herman, I., Weizman, A., & Yadid, G. (2006)

Dehydroepiandrosterone (DHEA) attenuates cocaine-seeking behavior in the self-administration model in rats

European Neuropsychopharmacology, 16(5), 329–339. https://doi.org/10.1016/j.euroneuro.2005.10.002
Ayalon, L., Doron, R., Weiner, I., & Joel, D. (2004)

Amelioration of behavioral deficits in a rat model of Huntington’s disease by an excitotoxic lesion to the globus pallidus

Experimental Neurology, 186(1), 46–58. https://doi.org/10.1016/S0014-4886(03)00312-1 (IF 4.544)